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KMID : 0880220070450040350
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Journal of Microbiology
2007 Volume.45 No. 4 p.350 ~ p.357
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Effect of Saliva miltiorrhiza Bunge on Antimicrobial Activity and Resistant Gene Regulation against Methicillin-Resistant Staphylococcus aureus (MRSA)
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Lee Ji-Won
Ji Young-Ju
Lee Syng-Ook
Lee In-Seon
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Abstract
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This study was conducted in an effort to evaluate the antimicrobial activity and antibiotic-resistant gene regulation from Saliva miltiorrhiza Bunge on methicillin-resistant Staphylococcus aureus (MRSA). A variety of solvent fractions and methanol extracts of S. miltiorrhiza Bunge were tested in order to determine its antimicrobial activities against S. aureus and MRSA. As a result, the hexane fraction of S. miltiorrhiza Bunge evidenced the highest levels of antimicrobial activity against S. aureus and MRSA. The MICs of the hexane fraction against various MRSA specimens were 64
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KEYWORD
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MRSA, Salvia miltiorrhiza Bunge, antimicrobial activity, resistant gene
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